Uses, Benefits, Side Effects & More


Inositol is a type of sugar that the body uses to make cell membranes. It also helps regulate insulin levels, which means it may have benefits for people with conditions such as metabolic syndrome and polycystic ovary syndrome (PCOS).

There are some evidence that inositol can also help with some mental health issues because it can affect neurotransmitters in the brain and nervous system.

The Food and Drug Administration (FDA) considers inositol to be generally safe, but some people may experience mild side effects if they take higher doses.

Read on to learn more about inositol, including what it is and its benefits, side effects, and food sources.

Inositol is a type of sugar similar to glucose. Humans can make it themselves or absorb it through their diet.

The body needs inositol to form structure of cell membranes and regulate insulin levels. This maybe also affect neurotransmitter levels. Neurotransmitters are chemicals that transmit messages between nerves.

There are nine forms of inositol, but the two main types in the body are myoinositol and D-chiro-inositol (DCI).

People take myoinositol supplements for a wide range of health reasons, many of which have supporting evidence. For example, people can use it to:

  • Mental Health
  • skin health
  • reproductive health
  • pregnancy health
  • metabolic health

Inositol may be especially beneficial for people with certain conditions.

Panic disorder

A study 2019 explored the effectiveness of a range of new drugs for treatment-resistant panic disorder. Researchers have found evidence that inositol is very effective in treating this disease. People taking inositol had fewer side effects than those taking selective serotonin reuptake inhibitors and benzodiazepines.

Bipolar disorder

A randomized controlled trial in The Journal of Clinical Psychiatry suggests that inositol may help treat bipolar disorder in children. The combination of omega-3 fatty acids and inositol reduced symptoms of mania and depression in children aged 5 to 12.

However, the study had a small number of participants, and researchers excluded children with serious conditions. More research is needed to confirm whether inositol helps people with bipolar disorder.


A Randomized placebo-controlled clinical trial 2020 found evidence to support the use of DCI to improve psoriasis symptoms. The researchers concluded that a solution containing 1% DCI could be a useful additional treatment for people with this condition.


PCOS causes production of the ovaries or adrenal glands excessive levels male sex hormones, which can affect fertility and insulin resistance.

A 2020 review found numerous studies demonstrating the effectiveness of inositol as a treatment for people with PCOS. Proven benefits included:

  • improve ovarian function and fertility
  • decrease levels of male sex hormones and thereby reduce the severity of acne and excessive hair growth
  • improve metabolic health
  • regulate hormones involved in reproduction and ovulation

Additionally, a Meta-analysis 2017 found significant reductions in fasting insulin in people with PCOS. The researchers concluded that myoinositol had a beneficial effect in improving the metabolic health of people with this condition.

Gestational Diabetes

Gestational Diabetes refers to high blood sugar during pregnancy. High blood sugar usually reverses after birth, but it can lead to pregnancy complications.

A study 2018 assessed whether myoinositol supplementation from the first trimester onwards had benefits for people at risk for gestational diabetes and its complications.

The researchers concluded that myoinositol supplementation in early pregnancy helps reduce the rate of gestational diabetes, premature birth, and high birth weight.

Metabolic syndrome

People with metabolic syndrome have several risk factors for cardiovascular disease and type 2 diabetes. These can include obesity, high blood pressure, and high blood sugar. According to a study 2022myoinositol affects this because it plays a role in blood sugar regulation.

Additionally, high glucose levels lower myoinositol levels in a person’s tissues. The body breaks down myoinositol faster and the kidneys eliminate it faster, creating a vicious cycle.

The authors of the study highlight the many studies demonstrating the safety of myoinositol. They conclude that doctors should consider it as a treatment for people with metabolic syndrome, as well as those with diabetes.

Many people can take inositol. The FDA classifies inositol as “generally recognized as safe”. However, some studies reviewed whether inositol is safe for babies and children.

Also, clinical trials on inositol tend to last no longer than a year, so it’s unclear if inositol can be taken safely long term.

People should speak with a doctor before trying inositol to verify that it is safe for them.

Clinical trials investigating the benefits of inositol tend to involve doses between 4g and 60g one day. To avoid side effects, people may benefit from a lower daily dose.

If a person is taking inositol for medical reasons, they should first consult a doctor. The doctor can advise you on the most suitable dosage.

An alternative to inositol supplementation is to get more of this substance from food. Although rare in modern diets, animal products The highest in inositol include:

  • kidney
  • brain
  • blood products

Other foods containing inositol include:

People can also eat foods that contain substances the body uses to make inositol, such as:

Inositol is a type of sugar that helps form the structure of cell membranes. It also regulates insulin and neurotransmitters. The human body can produce inositol, but people can also get it from supplements and certain foods.

Research suggests that inositol may benefit people with certain health conditions, including PCOS and metabolic syndrome. He seems to be generally safebut anyone who wants to try this supplement should discuss it with a doctor first.


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